Sometimes when you have few huge solutions opened performance of your PC is very critical and having Resharper over that is notable.

For our good luck with new versions of Resharper you could suspend it easily:

But going into menu is boring thing, so I think you would prefer to setup few hotkeys for that.

Basicly you will need to map Resharper_Suspend and/or Resharper_Resume. I bound those to “Ctrl+R, Ctrl+S” for Suspend and “Ctrl+R, Ctrl+R” for Resume.

Also, as I found over internet, JetBrains promise to have 5.1 being faster and without performance issues, but did not found any official words about this, just twits.

Personally I use Resharper Nightly Builds and enjoy them very much.

Hope this helps.